Friction Mediates Scission of Tubular Membranes Scaffolded by BAR Proteins
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چکیده
منابع مشابه
Friction Mediates Scission of Tubular Membranes Scaffolded by BAR Proteins
Membrane scission is essential for intracellular trafficking. While BAR domain proteins such as endophilin have been reported in dynamin-independent scission of tubular membrane necks, the cutting mechanism has yet to be deciphered. Here, we combine a theoretical model, in vitro, and in vivo experiments revealing how protein scaffolds may cut tubular membranes. We demonstrate that the protein s...
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ژورنال
عنوان ژورنال: Cell
سال: 2017
ISSN: 0092-8674
DOI: 10.1016/j.cell.2017.05.047